Padua University

 Padua University

Universita degli Studi di Padova
Ospedale 105
35128 Padova
Italy

http://www.unipd.it

Principal Investigator

Prof. Franco Mantero

Prof. Franco Mantero

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Institute Presentation

The Department of Medical and Surgical Sciences, Endocrine Unit has a long-lasting experience in the field of adrenal tumours. The Head of the Department, Prof. Franco Mantero is the national coordinator of the Italian Study Group of Adrenal Tumours (NISGAT).He and his group have conducted a number of collaborative epidemiological, clinical and therapeutic studies on the prevalence, pathophysiology and natural history of adrenocortical tumours, as well as molecular and genetic research, taking advantage of the local and satellite bio banks set-up by the NISGAT network. The Department of Immunology and molecular diagnosis in oncology of the Venetian Institute of Oncology (IOV) has a high scientific production and is responsible of the development, standardization and execution of molecular studies and innovative approaches to enable an advanced diagnostics, a follow-up and appropriate treatment of patients with solid and hematologic tumours. The head of the pathology group, Prof Fassina Ambrogio is responsible.

University of Padua will participate in WP2 and WP7. Main tasks of UNIPD within the project will consist of

  • Expansion of the local biobank to an ENS@T-ACC plasma biobank.
  • Evaluation of new therapeutic targets in xenograft models of adrenal tumours by testing mTOR/PI3K inhibitors for their ability to impair growth of ACC cells in vitro and in vivo.