Ludwig-Maximilians-University Munich

Ludwig-Maximilians-University Munich

Ludwig-Maximilians-University Munich

Ziemssenstr. 1
80336 München
Germany

http://www.med.uni-muenchen.de

Project Coordinator

Prof. Felix Beuschlein

Prof. Felix Beuschlein

Phone +49 89 5160 2110
Fax +49 89 5160 4467

http://www.endocrine-research.mki.klinikum.uni-muenchen.de

contact

Project Staff

Dr. Constanze Hantel

Dr. Constanze Hantel
Post-Doc, Ph.D. / tumor models

Phone +49 89 5160 4797
Fax +49 89 5160 4566

contact

 

Dr. Nicole Reisch

Dr. Nicole Reisch
Post-Doc, M.D. / clinical study (FIRSTMAPPP), registries

Phone +49 89 5160 2111
Fax +49 89 5160 4566

contact

Dr. Urs Lichtenauer

Dr. Urs Lichtenauer
Post-Doc, M.D. / clinical study (FIRSTMAPPP), registries

Phone +49 89 5160 2111
Fax +49 89 5160 4566

contact

Dr. Anna Pallauf

Dr. Anna Pallauf
Post-Doc, M.D.

Clinical study (ADIUVO), registries
Phone +49 89 5160 2111
Fax +49 89 5160 4566

contact

Igor Shapiro

Igor Shapiro
Technician / biosampling, in vitro studies

Phone +49 89 5160 2111
Fax +49 89 5160 4566

contact

Susanne Schmid

Susanne Schmid
Study nurse / clinical studies (FIRSTMAPPP, ADIUVO)

Phone +49 89 5160 2414
Fax +49 89 5160 2194

contact

Institute Presentation

The Medizinische Klinik Innenstadt is a tertiary referral centre for endocrine tumour patients. The department is devoted to translational research using its large patient cohorts and its numerous local, national and international collaborations. The department hosts a clinical study centre and basic science labs in the area of clinical chemistry, cellular and molecular biology and immunology. Prof. Beuschlein is the head of the Endocrine Research unit. His group has a long time experience with animal models in adrenal diseases focusing in particular on adrenal cancer. Specific local expertise in tumour preparation and primary cell culturing will be utilized to implement SOPs for the processing of surgical adrenocortical carcinoma specimen. These specimens will be used upon xenotransplantation as personalized tumour models. Local distribution with tumour material will be provided by Dr. Mussack from the Endocrine Surgery Unit. Furthermore, Dr. Bidlingmaier’s group is leading in assay development with special emphasis on multiplex technology using small sample analytes in rodent models. He will be in close collaboration for assay validation of newly identified biomarkers.

Prof. Beuschlein has been awarded multiple academic honours, awards and grants. He is a member of the Editorial Board of Journal of Molecular Endocrinology and ad hoc reviewer in multiple journals in the field. Prof. Beuschlein is Chairman of “Adrenal, Hypertension and Steroids” (Section of the German Endocrine Society) and Chairman of the Steering Committee of the European Network for the Study of Adrenal Tumours (ENS@T).

The Ludwig-Maximilians-University Munich leads the consortium, will be responsible for WP2 and participates in WP4, WP5, WP6, and WP7. The main tasks within the project will consist of

  • Validation of biomarkers for longitudinal follow-up, for risk profiles and for treatment response in personalized mouse models of malignant adrenal tumours
  • Exploration of BMP dependent pathways in ACC patients